Membrane Mosaic Bell Work Worksheet
NYS Life Science: Biology • NYSSLS HS-LS1-2
Membrane Mosaic Bell Work Review
Topic: Cell Membrane & Bilayer
5-Minute Daily Regents Warm-Ups
Student Name:
Date:
Period:
DAY 1
Phospholipid Anatomy & Spontaneous Bilayer Formation
Est. Time: 5 min
Phospholipid Structure & Arrangement
Extracellular Fluid (Aqueous / Water) Cytoplasm / Intracellular Fluid (Aqueous) Region A Region B Region C
Cross-section of plasma membrane
1. Identify the chemical properties of each labeled region in the diagram:
Region A (Phosphate Head):
Circle property: [ Polar / Nonpolar ]
Affinity: [ Hydrophilic / Hydrophobic ]
Region B (Fatty Acid Tails):
Circle property: [ Polar / Nonpolar ]
Affinity: [ Hydrophilic / Hydrophobic ]
2. Regents Reasoning: Both the intracellular fluid (cytoplasm) and extracellular fluid are primarily composed of water. Explain why the fatty acid tails spontaneously face inward toward each other rather than outward toward the fluid environments.
DAY 2
The Fluid Mosaic Model & Membrane Proteins
Est. Time: 5 min
Membrane Mosaic Architecture (High-Power Schematic)
Reference Diagram 2
1 2 Signal Molecule 3 4 4
1. Match each numbered structure above with its primary function:
Part 1: A. Cellular identification / immune recognition
Part 2: B. Maintains membrane fluidity at changing temperatures
Part 3: C. Channel/pump facilitating movement of polar ions/solutes
Part 4: D. Binds specific hormones or chemical signals
2. Cellular Communication: If a genetic mutation alters the tertiary amino acid shape of Structure 2, predict the effect on the target cell's ability to respond to its specific hormone. Explain why.
Regents Key Idea: Receptors and signal molecules operate via shape specificity (lock-and-key fit). Denaturation or structural changes prevent cellular communication!
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NYS Life Science: Biology Review • Bell Work (Continued)
Membrane Permeability & Regents Stimulus
DAY 3
Selective Permeability & Molecular Transport Across the Bilayer
Est. Time: 5 min
1. Complete the permeability audit table below. Classify how each substance crosses a healthy cell membrane:
| Substance |
Direct Bilayer Diffusion or Transport Protein? |
Scientific Reason (Size & Charge) |
| Oxygen Gas (\(O_2\)) & \(CO_2\) |
|
|
| Sodium Ion (\(Na^+\)) / \(K^+\) |
|
|
| Glucose (\(C_6H_{12}O_6\)) |
|
|
Membrane Concept Check:
Why is the plasma membrane referred to as "semi-permeable" or "selectively permeable" rather than completely permeable or impermeable?
DAY 4
NYS Regents Exam Stimulus Challenge
Est. Time: 5-7 min
Laboratory Scenario: Artificial Membrane Experiment
A biology student constructs an artificial cell using a pure phospholipid bilayer membrane containing no proteins. The artificial cell is placed in an aqueous beaker containing equal concentrations of dissolved starch molecules, glucose molecules, water, and oxygen gas. After 60 minutes, the internal and external solutions are analyzed using chemical indicators.
1. Predict which of the following substances will successfully diffuse into the protein-free artificial cell. (Circle all that apply)
A. Oxygen Gas
B. Starch Polymer
C. Glucose Monomer
D. Water (\(H_2O\))
2. In real biological cells, glucose enters via facilitated diffusion. State what specific membrane component must be inserted into the artificial cell membrane to permit glucose entry.
DAY 5
Weekly Synthesis & Misconception Check
Est. Time: 5 min
Evaluate each statement. Circle TRUE or FALSE. If false, write the correction in one brief sentence:
A. The cell membrane is rigid and static, preventing proteins from moving sideways within the bilayer. [ T / F ]
B. Hydrophilic phosphate heads interact directly with water in both the cytoplasm and extracellular space. [ T / F ]
Weekly Mastery Self-Rating
Rate your confidence on NYS Regents membrane questions:
1
Need Help
2
Getting It
3
Proficient
4
Regents Ready
Teacher Initial / Stamp: ______________
NYS Life Science: Biology Standards (NYSSLS) • Structure and Function of Cellular Membranes Page 2 of 2
