CHEM 1406 Review Package
CHEM 1406
Unit 4: Review Package
Name:
Date:
I. Vocabulary & Key Terms
Chiral Carbon:
Enantiomer:
Zwitterion:
Saponification:
N-Terminus:
II. Guided Concept Notes
A. Carbohydrates & Sugars
1. Carbohydrates are classified by their carbonyl group. An Aldose contains an aldehyde, while a ____________________ contains a ketone.
2. In a Fischer projection, if the OH group furthest from the carbonyl is on the left, it is the ________ isomer.
3. Glucose, also known as ____________________ or blood sugar, provides energy through the process of ____________________.
4. ____________________ is a condition where blood glucose levels are lower than normal.
B. Carboxylic Acids, Esters, & Amines
1. The reaction between a carboxylic acid and an alcohol produces an ____________________ and water. This is called esterification.
2. When an ester is split apart by acid and water, the process is called ____________________.
3. An amide is formed by the reaction of a ____________________ acid and an ____________________.
4. A ____________________ amine is an organic compound where the nitrogen is attached to three carbon groups.
C. Proteins & Amino Acids
1. Amino acids contain an ammonium group, a ____________________ group, and a unique ____________________ group.
2. At physiological pH, amino acids exist as ____________________ (dual ions).
3. Secondary structure like ____________________ sheets are held together by ____________________ bonding.
4. Tertiary structure is stabilized by interactions like ____________________ (ionic bonds between R groups) and ____________________ bridges (covalent).
III. Molecular Classification Map
Classify each functional group based on its structural components and primary reactions.
ESTERS
Draw general structure & list one reaction (e.g. hydrolysis)
AMIDES
Draw general structure & identify parent molecules
AMINO ACIDS
Identify the 4 functional groups around the alpha carbon
IV. Quick Summary Checklist
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Chirality Check: A carbon is chiral if it is bonded to four different groups.
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Sugar Suffixes: -ose = sugar. Aldohexose = 6 carbons + aldehyde. Ketopentose = 5 carbons + ketone.
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Solubility: Small polar molecules (1-4 carbons) are water soluble. Chains over 5 carbons are hydrophobic/insoluble.
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Protein Levels: Primary (sequence), Secondary (helices/sheets), Tertiary (3D folding), Quaternary (multiple chains).
CHEM 1406 Review Key
Answer Key
CHEM 1406 Review Package
Answer Key
I. Vocabulary & Key Terms
Chiral Carbon: A carbon atom bonded to four different atoms or groups of atoms.
Enantiomer: Stereoisomers that are nonsuperimposable mirror images of each other.
Zwitterion: A molecule with both positive and negative charges but a net charge of zero.
Saponification: The hydrolysis of an ester with a strong base to produce a salt of the carboxylic acid and an alcohol.
N-Terminus: The end of a peptide chain that has a free amino group (NH3+).
II. Guided Concept Notes
A. Carbohydrates & Sugars
1. Carbohydrates are classified by their carbonyl group. An Aldose contains an aldehyde, while a Ketose contains a ketone.
2. In a Fischer projection, if the OH group furthest from the carbonyl is on the left, it is the L isomer.
3. Glucose, also known as Dextrose or blood sugar, provides energy through the process of Respiration (Oxidation).
4. Hypoglycemia is a condition where blood glucose levels are lower than normal.
B. Carboxylic Acids, Esters, & Amines
1. The reaction between a carboxylic acid and an alcohol produces an Ester and water. This is called esterification.
2. When an ester is split apart by acid and water, the process is called Hydrolysis.
3. An amide is formed by the reaction of a Carboxylic acid and an Amine (or ammonia).
4. A Tertiary amine is an organic compound where the nitrogen is attached to three carbon groups.
C. Proteins & Amino Acids
1. Amino acids contain an ammonium group, a Carboxylate group, and a unique R (Side Chain) group.
2. At physiological pH, amino acids exist as Zwitterions (dual ions).
3. Secondary structure like beta-pleated sheets are held together by Hydrogen bonding.
4. Tertiary structure is stabilized by interactions like Salt Bridges (ionic bonds between R groups) and Disulfide bridges (covalent).
III. Molecular Classification Map
ESTERS
Structure: R-CO-OR'
Reactions: Acid Hydrolysis (Acid + Alcohol) or Saponification (Salt + Alcohol).
AMIDES
Structure: R-CO-NH2 (or NHR, NR2)
Parents: Formed from a Carboxylic Acid and an Amine (or ammonia).
AMINO ACIDS
4 Groups around Alpha Carbon:
- Hydrogen Atom (-H)
- Ammonium group (NH3+)
- Carboxylate group (COO-)
- R group (Specific side chain)
CHEM 1406 Review Exam
CHEM 1406
Unit 4: Review Exam
Name:
Date:
Instructions: Select the best alternative that completes the statement or answers the question.
- In biological systems, the oxidation of glucose primarily serves what function?
A) Storage of vitamins
B) Release of chemical energy
C) Synthesis of cell walls
D) Reduction of water
E) Mutarotation of starch
- Which organic product is formed when propanoic acid reacts with methylamine?
A) N-methylpropanamide
B) Methyl propanoate
C) Propanoyl chloride
D) Dimethylamine
E) Ethyl methyl ether
- At physiological pH (7.4), which part of an amino acid is typically negatively charged?
A) The alpha-hydrogen
B) The ammonium group
C) The carboxylate group
D) The thiol group
E) The methyl group
- What is the process called when an ester reacts with water in the presence of an acid catalyst?
A) Neutralization
B) Esterification
C) Saponification
D) Hydrolysis
E) Reduction
- What is the common name for the ester formed from acetic acid and ethanol?
A) Ethyl acetate
B) Methyl ethanoate
C) Butyl formate
D) Propyl acetate
E) Diethyl ester
- A monosaccharide with 6 carbon atoms and a ketone functional group is classified as a(n):
A) Aldohexose
B) Ketohexose
C) Ketopentose
D) Aldotetrose
E) Ketotetrose
- In a Fischer projection of an L-enantiomer, the hydroxyl group (-OH) furthest from the carbonyl is on which side?
A) Right side
B) Left side
C) Top side
D) Bottom side
E) Center
- Which of the following carbons is considered chiral?
A) Carbon with 2 H and 2 Cl
B) Carbon with 3 H and 1 OH
C) Carbon with 4 different groups
D) Carbon with a double bond
E) Carbon with 4 methyl groups
- What is the IUPAC name for a 4-carbon carboxylic acid with a chlorine atom on the 2nd carbon?