NYS Regents Prep Case #402

HOMEOSTASIS HACKERS

Mastering Claim, Evidence, & Reasoning through Biological Feedback

Student Name:

Date:

Class Period:

The Homeostasis Hack: Quick Notes

Homeostasis is your body's ability to maintain a stable internal environment despite changes in the outside world. To do this, your body uses feedback loops to detect changes and correct them.

1. Trigger

Eat a sugary donut

Blood sugar goes UP 📈

2. Sensor & Release

Pancreas releases INSULIN

Hormone acts like a key 🔑

3. Target & Fix

Cells absorb sugar

Sugar goes DOWN 📉

Part 1: CER Matching Training

Before writing your own CER, read this short scenario and match each statement below to its correct role.

Scenario: A student eats breakfast. Her blood glucose levels are measured every 30 minutes.

Time (minutes)	0 mins (Before Meal)	30 mins	60 mins	120 mins (After Meal)
Blood Glucose (mg/dL)	90 mg/dL	145 mg/dL	110 mg/dL	92 mg/dL

1 Which statement is the CLAIM that directly answers: "Does this student maintain homeostasis?"

The student's pancreas released a hormone called insulin to lower blood sugar levels. The student's blood glucose spiked to 145 mg/dL but returned to 92 mg/dL by 120 minutes. Yes, the student's body successfully maintained blood glucose homeostasis.

2 Which statement is the best biological EVIDENCE to support that claim?

The data table shows blood glucose levels went from 90 mg/dL up to 145 mg/dL, and then back down to 92 mg/dL at 120 minutes. Homeostasis is defined as the maintenance of a stable internal environment despite external changes. Glucose is a major energy source for cellular respiration, which produces ATP energy.

3 Which statement is the scientific REASONING that connects the evidence to the claim?

Eating food causes carbohydrate sugars to enter the bloodstream directly. When blood sugar rises, the pancreas secretes insulin. Insulin acts as a messenger, signaling body cells to absorb glucose, bringing levels back down to a stable state. The data table clearly shows that blood sugar went down from 145 mg/dL to 92 mg/dL.

Unit 4: Homeostasis and Feedback Mechanisms Page 1 of 2

Active Investigation File

THE HOMEOSTASIS CASE FILE

Investigate Patient B's feedback loop malfunction using evidence and science

CLINICAL FILE: PATIENT B (AGE 24)

Patient B was tested for diabetes. After fasting, they drank a high-glucose beverage. Doctors measured their blood glucose levels. In a healthy body, high blood sugar triggers the pancreas to release insulin to bring blood glucose back down to the normal resting range of 70 - 100 mg/dL.

Time (minutes)	0 mins (Fasting)	30 mins	60 mins	120 mins
Healthy Range (mg/dL)	70 - 100 mg/dL	120 - 140 mg/dL	100 - 120 mg/dL	70 - 100 mg/dL
Patient B Level (mg/dL)	110 mg/dL	185 mg/dL	195 mg/dL	180 mg/dL

Scientific Question: Does Patient B's body successfully maintain blood glucose homeostasis?

C 1. State Your Claim Answer the question in 1 full sentence.

💡 Choose an option to write down:

Option A: Patient B's body successfully maintains blood glucose homeostasis.

Option B: Patient B's body fails to maintain blood glucose homeostasis.

My Claim:

E 2. Provide Your Evidence Give at least TWO specific data points from the table above.

✍️ Sentence Starter help: "According to the data, at 0 minutes Patient B was... and at 120 minutes they were..."

My Evidence:

R 3. Explain Your Reasoning Connect evidence to claim. Explain the biological science behind the loop.

🧠 Fill-in-the-Blank Scientific Connection:

In a healthy body, high blood sugar triggers the pancreas to release insulin which lowers blood glucose. However, Patient B's level remains high at mg/dL at 120 minutes. This means their body fails to bring blood sugar back to the healthy range of mg/dL. This feedback malfunction is diagnosed as Diabetes.

My Biological Reasoning:

Unit 4: Homeostasis and Feedback Mechanisms Page 2 of 2

Homeostasis Hackers Worksheet

Homeostasis Hackers Worksheet

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